Warwickshire won the toss and elected to bat.
Stephen Harmison struck in his first over as Durham’s bowling attack started well.
Chris Rushworth collected the next wicket before Harmison struck again. Mitchell Claydon then entered the attack and collected three quick wickets as Warwickshire struggled to 52-6. Gareth Breese collected the seventh wicket as visitors stumbled to lunch at 86-7.
After lunch Stephen Harmison ensured no partnerships got built up as he collected the final three wickets to bowl Warwickshire out for 125.
S Harmison 5-22, Claydon 3-29, Breese 1-4, Rushworth 1-43.
Durham started the reply well reaching 52 before Will Smith was out for 31. A couple of wickets followed in quick succession as both Mustard and Coetzer were dismissed as Durham reached tea 88-3. Only four runs were added after tea before Michael Richardson was caught behind and Ben Harmison suffered the same fate.
Durham eventually succumbed to 161 all out. Warwickshire made it to the close on 19-0 after a day in which 20 wickets fell.
By lunch on day two the visitors were 131-2 and after the break Gareth Breese picked up his third catch of the day, this time off Rushworth, reducing the visitors to 152-4. Rushworth struck a second time the following over with a further 20 added to the total before Mitchell Claydon struck twice in quick succession with the total at 178.
Mark Wood claimed the seventh wicket with the score at 215 and then Claydon claimed his third wicket with the second new ball. Keaton Jennings cleared up the tail with the visitors posting 263.
Durham lost three scalps before the close with Mustard, Smith and Coetzer adding 83 between them before the end of day 2.
Early light showers delayed the start of play on the final day by 10 minutes but once play began Michael Richardson and Ben Harmison both passed the fifty mark and took the total to 157 before Harmison was run out at the non strikers end after a straight drive from Richardson flicked off the bowlers hand on tot the stumps.
Richardson (88) was dismissed with the score at 181-5 when he hit a full toss to mid on with 50 runs still required for the win.
Durham were seven down with 36 runs still required after Breese and Jennings were dismissed shortly after lunch but Ben Raine and Mark Wood steered the hosts to the win with three wickets in hand.